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產(chǎn)品中心抗體Polyclonal AntibodyK106633PAnti-EGLN Polyclonal Antibody
產(chǎn)品型號：K106633P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：883
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產(chǎn)品分類
Anti-EGLN Polyclonal Antibody
| 英文名稱 | Anti-EGLN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | ENG;END;CD105;Endoglin |
| 應(yīng)用 | IHC |
| 稀釋比例 | IHC 1:50-200. |
| 交叉反應(yīng) | Human |
| 蛋白分子量 | 71kDa |
| Gene ID | 2022 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human EGLN |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human EGLN |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P17813 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors. |
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